Paratuberculosis
Is the major cause of Functional Dyspepsia (FD), Irritable Bowel Syndrome (IBS) and Crohn's Disease (CD)
Mycobacterium Avium subsp. Paratuberculosis (MAP) infection?

Does MAP Cause Crohn's Disease?
Increasing Incidence of CD

A Prospective Epidemiologic Study of Crohn's Disease in Heraklion, Crete. Incidence Over a 5-year Period

Authors: Manousos ON, Koutroubakis I, Potamianos S, Roussomoustakaki M, Gourtsoyiannis N, Vlachonikolis IG.

Institution: Dept. of Gastroenterology, University Hospital of Heraklion, Greece.

Background: There has been an impression from published work that Crohn's disease is less common in southern than in northern Europe. A low incidence of Crohn's disease has been observed in Greece, but conclusive data are still lacking.

Results: The mean annual incidence of the disease for the years 1990-94 was 3.0 per 10(5) inhabitants. During the study period the incidence increased from 1.9/10(5) in 1990 to 3.8/10(5) in 1994. The male to female ratio was 2.4:1. The age group 25-34 years had the highest age-adjusted incidence (6.3/10(5)). The incidence of Crohn's disease was also found to be higher in smokers, in urban areas, and in people with high educational level.

Conclusion: Crohn's disease is common in Heraklion, Crete. The findings of the study are discussed in relation to those of other European countries.

Study link: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8789900&query_hl=2


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