Authors: Balsari A, Ceccarelli A, Dubini F, Fesce E, Poli G.

Summary: The focal microbial flora composition has been studied in patients affected by irritable bowel syndrome. The statistical analysis of the results showed a decrease of coliforms, lactobacilli and, to a lesser extent, bifidobacteria, as compared to control healthy individuals. Hypotheses on the cause of these modifications and their role in the maintenance and severity of the disease are discussed.

Study link: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7121297&dopt=Abstract

• Analysis of the Fecal Microbiota of Irritable Bowel Syndrome Patients and Healthy Controls with Real-Time PCR
• A Review of the Role of the Gut Microflora in Irritable Bowel Syndrome and the Effects of Probiotics
• Alteration of Intestinal Microflora is Associated with Reduction in Abdominal Bloating and Pain in Patients with Irritable Bowel Syndrome
• Do Interventions which Reduce Colonic Bacterial Fermentation Improve Symptoms of Irritable Bowel Syndrome?