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Pre-illness Dietary Factors in Inflammatory Bowel Disease

Authors: Reif S, Klein I, Lubin F, Farbstein M, Hallak A, Gilat T.

Institution: Department of Gastroenterology, Tel Aviv Sourasky Medical Center, Israel.

Background: The effect of environmental factors has been demonstrated in the pathogenesis of inflammatory bowel disease (IBD). Nutrition may be one of them.

AIM: To investigate the pre-illness diet in patients with recent IBD in comparison with matched population and clinic controls.

Results: A high sucrose consumption was associated with an increased risk for IBD (OR 2.85 (p = 0.03) against population controls and 5.3 (p = 0.00) against clinic controls). Lactose consumption showed no effect while fructose intake was negatively associated with risk for IBD (NS). Similar trends were noted in UC and CD…

Conclusions: An association was found between pre-illness diet and subsequent development of UC and CD. The effect of dietary components may be primary or modulatory.

Study link: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9245929&query_hl=9


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